Patient Support & Adherence Tech Vendors
Technology platforms for patient engagement, adherence, digital enrollment and e-services connectivity.
33 vendors profiled
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New York, NY
AdhereTech makes the Aidia System, a cellular-connected smart pill bottle and intervention platform that tracks specialty medication use in real time and triggers reminders and live support, typically funded by pharma brands and specialty pharmacies. Founded in 2011 and headquartered in New York.
- Aidia smart bottle and smart cap
- real-time adherence monitoring
- patient reminders and interventions
- clinical trial adherence devices
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New York, NY
AllazoHealth applies AI to predict individual medication behavior and optimize the content, channel, timing, and frequency of patient support communications for pharma brands, improving initiation and adherence. Its assets were acquired by AssistRx in April 2025.
- AI adherence targeting
- content and channel optimization
- dynamic modular patient emails
- patient support program personalization
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Cranberry Township, PA
Annexus Health offers AssistPoint, a software platform used across 4,200+ sites of care to find, enroll in, and manage copay, foundation, and PAP financial assistance, plus Adparo tech-enabled services and AP Connect links to pharma patient support programs. Founded in 2017 near Pittsburgh.
- AssistPoint financial assistance workflow platform
- assistance program search and e-enrollment
- award tracking and monitoring
- AP Connect pharma PSP integration
- Adparo patient assistance services
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Denver, CO
Arrive Health (formerly RxRevu) delivers real-time, patient-specific prescription cost, coverage, and prior authorization data into EHR prescribing workflows to improve affordability and adherence. Founded in 2013 in Denver, it reaches 300,000 providers and 150 million patients.
- real-time prescription benefit checks
- EHR-embedded price transparency
- prior authorization insights
- medication adherence technology
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Orlando, FL
AssistRx provides a technology-first specialty therapy initiation and patient support platform (including iAssist and Advanced Gateway) for life sciences companies, offering e-enrollment, electronic benefit verification, e-prior authorization, and patient engagement. Founded in 2009 and headquartered in Orlando, FL.
- therapy initiation technology (iAssist)
- Advanced Gateway single-API access solution
- e-benefit verification
- electronic prior authorization
- patient support program technology
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Seattle, WA
Atlas Health is an AI-powered patient affordability platform that matches patients to 7,000+ philanthropic and manufacturer assistance funding sources and automates enrollment and award management for health systems. Based in Seattle, it raised a $40M Series A led by Felicis Ventures in 2022.
- philanthropic aid matching (AI)
- medication assistance program automation (Atlas MAP)
- enrollment automation
- award and claims tracking
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Bethesda, MD
CareMetx is a technology-enabled digital hub platform for specialty medications, providing e-enrollment, electronic benefit verification, prior authorization support, and workflow tools for reimbursement case managers and field reimbursement teams. Headquartered in Bethesda, Maryland.
- digital hub platform
- electronic benefit verification
- e-enrollment and e-consent
- prior authorization support
- patient access data and analytics
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New York, NY
Cecelia Health operates a 50-state virtual specialty clinic delivering clinician-led patient support programs for pharma and device manufacturers, combining digital engagement with nurses, dietitians, and diabetes educators to improve initiation, adherence, and persistence. Active since 2009 (originally Fit4D).
- virtual clinical patient support programs
- medication adherence coaching
- device onboarding and titration support
- virtual specialty care
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Whippany, NJ
ConnectiveRx provides copay and voucher programs, hub services, and affordability/adherence messaging for pharmaceutical brands, spanning 140+ manufacturers and 550+ brands. Through its PSKW heritage it pioneered pharmacy-processed copay programs and delivers affordability messaging through EHR networks.
- copay card programs
- voucher programs
- EHR affordability messaging
- hub services
- medical claims processing
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New York, NY
Courier Health builds a patient CRM and engagement platform purpose-built for biopharma patient services teams, unifying patient, hub, and specialty pharmacy data to orchestrate access, affordability, and adherence workflows. Founded in 2021 in New York City.
- patient CRM for life sciences
- patient support program orchestration
- omnichannel engagement workflows
- AI workflow automation
- data integrations and analytics
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Columbus, OH
CoverMyMeds automates electronic prior authorization and medication access workflows connecting providers, pharmacies, payers, and pharma manufacturers. Founded in 2008 and acquired by McKesson for $1.1B in 2017, it is one of the largest ePA networks in the US.
- electronic prior authorization
- real-time benefit check
- specialty patient support technology
- affordability solutions
- e-enrollment
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San Francisco, CA
Develop Health is a GenAI-native platform that automates pharmacy-benefit verification and the full prior authorization cycle (submission, follow-up, denials, appeals) inside EHR and virtual care workflows. It raised $14.3M in August 2025 and supports hundreds of thousands of patients monthly.
- AI benefit verification
- automated prior authorization and appeals
- real-time coverage and out-of-pocket estimates
- EHR integrations (athenahealth)
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Rockville, MD
DrFirst provides medication management technology including e-prescribing, electronic prior authorization, price transparency, and patient medication adherence engagement programs that reach roughly 60 million patients annually. Founded in 2000 and headquartered in Rockville, Maryland.
- electronic prior authorization
- real-time benefit and price transparency
- patient adherence messaging
- e-prescribing infrastructure
- medication history
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Louisville, KY
eBlu Solutions provides a single-portal platform for real-time benefit investigation, electronic prior authorization, and manufacturer savings program enrollment for infusion and injection specialty therapies, supporting 1,200+ payers. Founded in 2012 in Louisville, KY; acquired in 2025 and rebranded as CareTria Provider Connect in April 2026.
- real-time benefit investigation
- electronic prior authorization
- medical and pharmacy benefit support
- manufacturer savings program connectivity
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San Francisco, CA
Infinitus builds voice AI agents that automate payer phone calls for benefit verification, prior authorization follow-up, and claims workflows on behalf of pharma patient support programs, specialty pharmacies, and providers. Its AI agents have powered 100M+ minutes of healthcare conversations.
- AI-automated benefit verification calls
- prior authorization follow-up automation
- PBM discovery
- structured payer data output for hub workflows
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Boston, MA
Medisafe is a digital medication management platform offering white-label Digital Drug Companions for pharma brands, driving adherence and persistence through personalized patient engagement, reminders, and connected support. Founded in 2012 and based in Boston, its programs have shown a 15% persistence lift on specialty medicines.
- digital drug companion apps
- medication reminders and engagement
- omnichannel patient support
- adherence analytics
- SDK/platform for pharma
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San Diego, CA
Medvantx administers patient assistance program (PAP) fulfillment, bridge/quick-start, and product replacement programs for pharma manufacturers via licensed 50-state central-fill pharmacies in Sioux Falls, SD and Louisville, KY. It partners with 5 of the 10 largest US pharmaceutical manufacturers.
- PAP fulfillment and administration
- bridge and quick-start programs
- central fill pharmacy
- telehealth fulfillment
- cold chain dispensing
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Mesa, AZ
Myndshft provides real-time medical and pharmacy benefit verification and automated prior authorization SaaS covering 95% of insured US patients and 600+ payers. Founded in 2018, its assets were acquired by DrFirst in April 2024.
- real-time medical benefit checks
- automated prior authorization
- eligibility verification
- payer rules engine
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Rochester, MI
OptimizeRx (Nasdaq: OPRX) delivers digital affordability, access, and adherence messaging for pharma brands within EHR and point-of-care workflows, reaching over 60% of US healthcare providers. Founded in 2006 and headquartered in Rochester, Michigan.
- digital copay/affordability messaging at point of care
- EHR-based access communications
- AI-driven HCP targeting (Dynamic Audience Activation Platform)
- hub enrollment digitization
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Henderson, NV
Paysign (Nasdaq: PAYS) provides prepaid card and payments infrastructure for pharma patient affordability programs, including pharmacy-adjudicated copay solutions and dynamic business rules that mitigate copay accumulator and maximizer programs. Founded in 2001 and headquartered in Henderson, Nevada.
- copay card programs and adjudication
- prepaid payment cards
- accumulator/maximizer mitigation (Dynamic Business Rules)
- patient support call center
- patient affordability analytics
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Columbia, MO
Paytient provides Health Payment Accounts (HPAs) that let patients pay medical and pharmacy out-of-pocket costs over time with zero-interest installments, distributed through employers, insurers, and PBMs. Founded in 2018 in Columbia, Missouri, it serves 23M+ members.
- Health Payment Account (HPA)
- interest-free medical/pharmacy payment plans
- Medicare Part D M3P payment technology
- employer and health plan benefit integration
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Chicago, IL
Perx Health offers a mobile engagement platform using gamification, rewards, and behavioral nudges to drive medication adherence (80-85% reported rates) for health plans and care programs. Australian-founded with US operations headquartered in Chicago; its US business was acquired by Clutch Health in May 2026.
- gamified adherence programs
- personalized incentives and rewards
- daily engagement nudges
- chronic condition self-management
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San Francisco, CA
Phil (PHIL Inc.) is a software-driven digital hub and direct-to-patient platform that helps pharma brands maximize prescription starts, coverage, and adherence through automated access and fulfillment workflows. Founded in 2015 in San Francisco, it has raised roughly $100M in venture funding.
- digital hub services
- prescription access and fulfillment orchestration
- copay program management
- direct-to-patient distribution
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New York, NY
Pleio runs the GoodStart program, a white-label peer-to-patient outreach service in which trained mentors call patients at medication start to address emotional barriers to adherence, sold to pharma brands and pharmacies. Founded in 2007 with headquarters in New York.
- GoodStart peer mentor onboarding calls
- medication adherence support
- pharmacy-integrated patient engagement
- behavioral/emotional barrier programs
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Madison, WI
Propeller Health provides connected inhaler sensors and companion digital experiences for asthma and COPD, running commercial digital medicine programs with pharma partners including GSK, Novartis, and Boehringer Ingelheim. Acquired by ResMed for $225M in 2019; offices in Madison, WI and San Francisco.
- connected inhaler sensors
- respiratory adherence programs
- pharma co-commercialization programs
- digital therapeutics analytics
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New Albany, IN
Digital platform that automates specialty medication enrollment, benefit checks, prior authorization, consent collection, and patient assistance program applications for providers, hubs, and manufacturers. Acquired by CoverMyMeds (McKesson) in June 2025.
- digital specialty enrollment
- benefit verification
- electronic prior authorization
- digital consent
- PAP application automation
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San Francisco, CA
Medical-benefit prior authorization platform used by physician practices to submit, track, and manage prior authorizations for buy-and-bill specialty drugs; pharma manufacturers sponsor the platform to reduce access friction for their brands.
- medical benefit prior authorization workflow
- benefit verification
- enrollment support
- brand-sponsored access programs
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Baltimore, MD
Scene Health (formerly emocha Health) scales video Directly Observed Therapy: patients submit daily medication videos reviewed by a care team of pharmacists, nurses, and coaches to verify and improve adherence. Based in Baltimore, it serves health plans, public health programs, and research organizations.
- video directly observed therapy (DOT)
- medication engagement programs
- adherence coaching
- public health medication programs
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San Francisco, CA
Sempre Health offers SMS-based, behavior-based dynamic medication pricing: patients earn lower copays for on-time refills, with programs funded through pharma and PBM/health plan partnerships covering roughly 150 million commercial lives. Founded in 2015 in San Francisco.
- dynamic behavior-based copay pricing
- SMS refill engagement
- Medicare adherence incentive programs
- pharmacy counter savings notifications
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Arlington, VA
Surescripts operates the largest US e-prescribing network and provides electronic prior authorization (including Touchless PA) and Real-Time Prescription Benefit price transparency used across prescriber, pharmacy, and PBM workflows. Its network reaches hundreds of thousands of prescribers nationwide.
- e-prescribing network
- electronic prior authorization
- Real-Time Prescription Benefit
- medication history
- specialty patient enrollment
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New York, NY
TailorMed operates a financial navigation and medication affordability platform that identifies at-risk patients and automatically matches and enrolls them across 6,000+ assistance programs, including manufacturer copay and PAP resources. Its network spans 945+ hospitals, 4,700+ clinics, and 3,100+ pharmacies.
- financial navigation software
- assistance program matching and auto-enrollment
- benefit investigation
- out-of-pocket cost estimation
- life sciences affordability network
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Morrisville, NC / Jeffersonville, IN
Valeris was formed in May 2025 through the merger of Mercalis (formerly TrialCard, a pioneer of copay card administration) and PharmaCord, combining copay/affordability programs, patient assistance program administration, hub services, and non-commercial pharmacy for 500+ life sciences customers.
- copay assistance program administration
- patient assistance program administration
- patient support hub services
- non-commercial pharmacy
- market access analytics
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Los Angeles, CA
Wellth uses behavioral economics and daily financial incentives (loss aversion) delivered via smartphone check-ins to improve medication adherence and care plan compliance, primarily for health plans and at-risk providers with pharma-adjacent applications. Founded in 2014.
- incentive-based medication adherence programs
- daily photo check-in verification
- chronic condition engagement
- adherence analytics
